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{{STRUCTURE_3r3x|  PDB=3r3x  |  SCENE=  }}
===Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Bromoacetate===
{{ABSTRACT_PUBMED_21510690}}


==Function==
==Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Bromoacetate==
[[http://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
<StructureSection load='3r3x' size='340' side='right'caption='[[3r3x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3r3x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R3X FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BXA:BROMOACETIC+ACID'>BXA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r3x OCA], [https://pdbe.org/3r3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r3x RCSB], [https://www.ebi.ac.uk/pdbsum/3r3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r3x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>  


==About this Structure==
==See Also==
[[3r3x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R3X OCA].
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:021510690</ref><references group="xtra"/><references/>
__TOC__
[[Category: Haloacetate dehalogenase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodopseudomonas palustris]]
[[Category: Rhodopseudomonas palustris]]
[[Category: Chan, P W.Y.]]
[[Category: Chan PWY]]
[[Category: Edwards, E A.]]
[[Category: Edwards EA]]
[[Category: Pai, E F.]]
[[Category: Pai EF]]
[[Category: Yakunin, A F.]]
[[Category: Yakunin AF]]
[[Category: Alpha/beta hydrolase]]
[[Category: Defluorinase]]
[[Category: Facd]]
[[Category: Hydrolase]]

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