3qyo: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qyo is ON HOLD Authors: Collins, E.J., Lee, A.L., Carroll, M.J., Mauldin, R.V., Gromova, A.V., Singleton, S.F. Description: Sensitivity of recepto... |
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==Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate== | |||
<StructureSection load='3qyo' size='340' side='right'caption='[[3qyo]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qyo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QYO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=Q24:QUINAZOLINE-2,4-DIAMINE'>Q24</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qyo OCA], [https://pdbe.org/3qyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qyo RCSB], [https://www.ebi.ac.uk/pdbsum/3qyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qyo ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==See Also== | |||
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Carroll MJ]] | |||
[[Category: Collins EJ]] | |||
[[Category: Gromova AV]] | |||
[[Category: Lee AL]] | |||
[[Category: Mauldin RV]] | |||
[[Category: Singleton SF]] | |||
Latest revision as of 13:50, 21 February 2024
Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rateSensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate
Structural highlights
FunctionDYR_ECOLI Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also |
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