3qrr: Difference between revisions
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New page: '''Unreleased structure''' The entry 3qrr is ON HOLD Authors: Schellenberg, M.J., Gesner, E.G., Garside E.L., MacMillan, A.M. Description: Structure of Thermus Thermophilus Cse3 bound ... |
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==Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex== | |||
<StructureSection load='3qrr' size='340' side='right'caption='[[3qrr]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qrr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.099Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrr OCA], [https://pdbe.org/3qrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrr RCSB], [https://www.ebi.ac.uk/pdbsum/3qrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAS6_THET8 CAS6_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref> | |||
==See Also== | |||
*[[CRISPR type I-E (Cascade)|CRISPR type I-E (Cascade)]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermus thermophilus HB8]] | |||
[[Category: Garside EL]] | |||
[[Category: Gesner EG]] | |||
[[Category: MacMillan AM]] | |||
[[Category: Schellenberg MJ]] | |||
Latest revision as of 13:49, 21 February 2024
Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complexStructure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex
Structural highlights
FunctionCAS6_THET8 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.[1] [2] See AlsoReferences
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