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==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor== | ==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor== | ||
<StructureSection load='3q5k' size='340' side='right' caption='[[3q5k]], [[Resolution|resolution]] 2.35Å' scene=''> | <StructureSection load='3q5k' size='340' side='right'caption='[[3q5k]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5K FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5k OCA], [https://pdbe.org/3q5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5k RCSB], [https://www.ebi.ac.uk/pdbsum/3q5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5k ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q4Q4I6_LEIMA Q4Q4I6_LEIMA] | |||
==See Also== | |||
*[[Heat Shock Protein structures|Heat Shock Protein structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Leishmania major]] | ||
[[Category: Bountra | [[Category: Arrowsmith CH]] | ||
[[Category: Cossar | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Cossar D]] | ||
[[Category: Fairlamb | [[Category: Edwards AM]] | ||
[[Category: Ferguson | [[Category: Fairlamb A]] | ||
[[Category: Hills | [[Category: Ferguson MAJ]] | ||
[[Category: Hui | [[Category: Hills T]] | ||
[[Category: Hutchinson | [[Category: Hui R]] | ||
[[Category: Lin | [[Category: Hutchinson A]] | ||
[[Category: MacKenzie | [[Category: Lin YH]] | ||
[[Category: Pizarro | [[Category: MacKenzie F]] | ||
[[Category: Pizarro JC]] | |||
[[Category: Schapira | [[Category: Schapira M]] | ||
[[Category: Tempel | [[Category: Tempel W]] | ||
[[Category: Weigelt | [[Category: Weigelt J]] | ||
[[Category: Wernimont | [[Category: Wernimont AK]] | ||
[[Category: Zhao | [[Category: Zhao Y]] | ||