3pw4: Difference between revisions

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-[[Image:3pw4.png|left|200px]]
-<!--
+==Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dATP==
-The line below this paragraph, containing "STRUCTURE_3pw4", creates the "Structure Box" on the page.
+<StructureSection load='3pw4' size='340' side='right'caption='[[3pw4]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3pw4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PW4 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AFN:8,9-DIHYDRO-9-HYDROXY-AFLATOXIN+B1'>AFN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene></td></tr>
-{{STRUCTURE_3pw4|  PDB=3pw4  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pw4 OCA], [https://pdbe.org/3pw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pw4 RCSB], [https://www.ebi.ac.uk/pdbsum/3pw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pw4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
-===Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dATP===
+==See Also==
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_21790157}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 21790157 is the PubMed ID number.
+[[Category: Saccharolobus solfataricus]]
--->
+[[Category: Synthetic construct]]
-{{ABSTRACT_PUBMED_21790157}}
+[[Category: Banerjee S]]
-==About this Structure==
-[[3pw4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PW4 OCA].
-==Reference==
-<ref group="xtra">PMID:021790157</ref><references group="xtra"/>
-[[Category: DNA-directed DNA polymerase]]
-[[Category: Sulfolobus solfataricus]]
-[[Category: Banerjee, S.]]
-[[Category: Dna adduct]]
-[[Category: Dna polymerase]]
-[[Category: Ternary complex of dpo4-dna-datp]]
-[[Category: Transferase-dna complex]]