3pgl: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 3pgl is ON HOLD
+==Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole==
+<StructureSection load='3pgl' size='340' side='right'caption='[[3pgl]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3pgl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PGL FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RZX:2-[(R)-{[4-(3-METHOXYPROPOXY)-3-METHYLPYRIDIN-2-YL]METHYL}SULFINYL]-1H-BENZIMIDAZOLE'>RZX</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pgl OCA], [https://pdbe.org/3pgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pgl RCSB], [https://www.ebi.ac.uk/pdbsum/3pgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pgl ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CTDS1_HUMAN CTDS1_HUMAN] Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.<ref>PMID:12721286</ref> <ref>PMID:15681389</ref>
-Authors: Zhang, M., Cho, E.J., Burstein, G., Siegel, D., Zhang, Y.
+==See Also==
+*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
-Description: Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole
+== References ==
+<references/>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:33:01 2010''
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Burstein G]]
+[[Category: Cho EJ]]
+[[Category: Siegel D]]
+[[Category: Zhang M]]
+[[Category: Zhang Y]]