3ox2: Difference between revisions

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-[[Image:3ox2.png|left|200px]]
-<!--
+==X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values==
-The line below this paragraph, containing "STRUCTURE_3ox2", creates the "Structure Box" on the page.
+<StructureSection load='3ox2' size='340' side='right'caption='[[3ox2]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ox2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OX2 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=79X:2-HYDROXY-8,9-DIMETHOXY-6H-ISOINDOLO[2,1-A]INDOL-6-ONE'>79X</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_3ox2|  PDB=3ox2  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ox2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ox2 OCA], [https://pdbe.org/3ox2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ox2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ox2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ox2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
-===X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values===
+==See Also==
+*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_21538647}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 21538647 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_21538647}}
-==About this Structure==
-[[3ox2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OX2 OCA].
-==Reference==
-<ref group="xtra">PMID:021538647</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Mesecar, A D.]]
+[[Category: Large Structures]]
-[[Category: Pegan, S D.]]
+[[Category: Mesecar AD]]
-[[Category: Sturdy, M.]]
+[[Category: Pegan SD]]
-[[Category: Fad]]
+[[Category: Sturdy M]]
-[[Category: Flavoprotein]]
-[[Category: Metal-2 binding]]
-[[Category: Nq02]]
-[[Category: Oxidoreductase]]
-[[Category: Phosphoprotein]]
-[[Category: Qr2]]