3ouy: Difference between revisions

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'''Unreleased structure'''


The entry 3ouy is ON HOLD
==How the CCA-adding Enzyme Selects Adenine Over Cytosine at Position 76 of tRNA==
<StructureSection load='3ouy' size='340' side='right'caption='[[3ouy]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ouy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OUY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.69&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ouy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ouy OCA], [https://pdbe.org/3ouy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ouy RCSB], [https://www.ebi.ac.uk/pdbsum/3ouy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ouy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref>


Authors: Pan, B.C., Xiong, Y., Steitz, T.A.
==See Also==
 
*[[CCA-adding enzyme 3D structures|CCA-adding enzyme 3D structures]]
Description: How the CCA-adding Enzyme Selects Adenine Over Cytosine at Position 76 of tRNA
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
 
== References ==
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:57:24 2010''
<references/>
__TOC__
</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Large Structures]]
[[Category: Pan BC]]
[[Category: Steitz TA]]
[[Category: Xiong Y]]

Latest revision as of 13:36, 21 February 2024

How the CCA-adding Enzyme Selects Adenine Over Cytosine at Position 76 of tRNAHow the CCA-adding Enzyme Selects Adenine Over Cytosine at Position 76 of tRNA

Structural highlights

3ouy is a 4 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.69Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CCA_ARCFU Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.[1]

See Also

References

  1. Okabe M, Tomita K, Ishitani R, Ishii R, Takeuchi N, Arisaka F, Nureki O, Yokoyama S. Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure. EMBO J. 2003 Nov 3;22(21):5918-27. PMID:14592988 doi:http://dx.doi.org/10.1093/emboj/cdg563

3ouy, resolution 2.69Å

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