3nbq: Difference between revisions

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-{{Seed}}
-[[Image:3nbq.png|left|200px]]
-<!--
+==Human uridine phosphorylase 1 (hUPP1) with 5-fluorouracil==
-The line below this paragraph, containing "STRUCTURE_3nbq", creates the "Structure Box" on the page.
+<StructureSection load='3nbq' size='340' side='right'caption='[[3nbq]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3nbq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NBQ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=URF:5-FLUOROURACIL'>URF</scene></td></tr>
-{{STRUCTURE_3nbq|  PDB=3nbq  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nbq OCA], [https://pdbe.org/3nbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nbq RCSB], [https://www.ebi.ac.uk/pdbsum/3nbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nbq ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/UPP1_HUMAN UPP1_HUMAN] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nb/3nbq_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nbq ConSurf].
+<div style="clear:both"></div>
-===Human uridine phosphorylase 1 (hUPP1) with 5-fluorouracil===
+==See Also==
+*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_20856879}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 20856879 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_20856879}}
-==About this Structure==
-NBQ is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBQ OCA].
-==Reference==
-<ref group="xtra">PMID:20856879</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Uridine phosphorylase]]
+[[Category: Large Structures]]
-[[Category: Roosild, T P.]]
+[[Category: Roosild TP]]
-[[Category: 5-fluorouracil]]
-[[Category: Chemotherapy]]
-[[Category: Nucleoside phosphorylase]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:10:19 2010''