3n4p: Difference between revisions

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'''Unreleased structure'''


The entry 3n4p is ON HOLD  until Paper Publication
==Human cytomegalovirus terminase nuclease domain==
<StructureSection load='3n4p' size='340' side='right'caption='[[3n4p]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3n4p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_Towne Human herpesvirus 5 strain Towne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N4P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n4p OCA], [https://pdbe.org/3n4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n4p RCSB], [https://www.ebi.ac.uk/pdbsum/3n4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n4p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/3n4p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n4p ConSurf].
<div style="clear:both"></div>


Authors: Nadal, M., Mas, P.J., Blanco, A.G., Arnan, C., Sola, M., Hart, D.J., Coll, M.
==See Also==
 
*[[Terminase 3D Structures|Terminase 3D Structures]]
Description: Human cytomegalovirus terminase nuclease domain
__TOC__
 
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:30:30 2010''
[[Category: Human herpesvirus 5 strain Towne]]
[[Category: Large Structures]]
[[Category: Arnan C]]
[[Category: Blanco AG]]
[[Category: Coll M]]
[[Category: Hart DJ]]
[[Category: Mas PJ]]
[[Category: Nadal M]]
[[Category: Sola M]]

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