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New page: '''Unreleased structure''' The entry 3lp6 is ON HOLD Authors: Kim, H., Yu, M., Hung, L.-W., Terwilliger, T.C., Kim, C.-Y. Description: Crystal Structure of Rv3275c-E60A from Mycobacter... |
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==Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution== | |||
<StructureSection load='3lp6' size='340' side='right'caption='[[3lp6]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3lp6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LP6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.702Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lp6 OCA], [https://pdbe.org/3lp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lp6 RCSB], [https://www.ebi.ac.uk/pdbsum/3lp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lp6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PURE_MYCTU PURE_MYCTU] Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/3lp6_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lp6 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Phosphoribosylaminoimidazole carboxylase 3D structures|Phosphoribosylaminoimidazole carboxylase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Hung L-W]] | |||
[[Category: Kim C-Y]] | |||
[[Category: Kim H]] | |||
[[Category: Terwilliger TC]] | |||
[[Category: Yu M]] | |||
Latest revision as of 13:21, 21 February 2024
Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolutionCrystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution
Structural highlights
FunctionPURE_MYCTU Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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