3l1e: Difference between revisions

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{{STRUCTURE_3l1e|  PDB=3l1e  |  SCENE=  }}
===Bovine AlphaA crystallin Zinc Bound===
{{ABSTRACT_PUBMED_20440841}}


==Function==
==Bovine AlphaA crystallin Zinc Bound==
[[http://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN]] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.  
<StructureSection load='3l1e' size='340' side='right'caption='[[3l1e]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3l1e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The July 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L1E FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l1e OCA], [https://pdbe.org/3l1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l1e RCSB], [https://www.ebi.ac.uk/pdbsum/3l1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l1e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/3l1e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l1e ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
[[3l1e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The July 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1E OCA].
*[[Crystallin 3D structures|Crystallin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020440841</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Crystallins]]
[[Category: Crystallins]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Cascio, D.]]
[[Category: Cascio D]]
[[Category: Eisenberg, D.]]
[[Category: Eisenberg D]]
[[Category: Laganowsky, A.]]
[[Category: Laganowsky A]]
[[Category: Sawaya, M R.]]
[[Category: Sawaya MR]]
[[Category: Chaperone]]
[[Category: Crystallin]]
[[Category: Eye lens protein]]
[[Category: Lens transparency]]
[[Category: Polydispersity]]
[[Category: Protein aggregation]]

Latest revision as of 13:19, 21 February 2024

Bovine AlphaA crystallin Zinc BoundBovine AlphaA crystallin Zinc Bound

Structural highlights

3l1e is a 1 chain structure with sequence from Bos taurus. The July 2010 RCSB PDB Molecule of the Month feature on Crystallins by David Goodsell is 10.2210/rcsb_pdb/mom_2010_7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.15Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CRYAA_BOVIN May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3l1e, resolution 1.15Å

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