3kyh: Difference between revisions

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[[Image:3kyh.jpg|left|200px]]


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==Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus==
The line below this paragraph, containing "STRUCTURE_3kyh", creates the "Structure Box" on the page.
<StructureSection load='3kyh' size='340' side='right'caption='[[3kyh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3kyh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The January 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Messenger RNA Capping''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_1 10.2210/rcsb_pdb/mom_2012_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KYH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyh OCA], [https://pdbe.org/3kyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kyh RCSB], [https://www.ebi.ac.uk/pdbsum/3kyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyh ProSAT]</span></td></tr>
{{STRUCTURE_3kyh|  PDB=3kyh  |  SCENE=  }}
</table>
 
== Function ==
===Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus===
[https://www.uniprot.org/uniprot/CET1_YEAST CET1_YEAST] First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.<ref>PMID:12788946</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
3KYH is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYH OCA].  
  <jmolCheckbox>
[[Category: Polynucleotide 5'-phosphatase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kyh ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Messenger RNA Capping]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Lima, C D.]]
[[Category: Lima CD]]
[[Category: 5' modification]]
[[Category: Capping]]
[[Category: Complex]]
[[Category: Gtp-binding]]
[[Category: Guanylyltransferase]]
[[Category: Hydrolase]]
[[Category: Mrna capping]]
[[Category: Mrna processing]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein binding]]
[[Category: Rna]]
[[Category: Transferase]]
[[Category: Triphosphatase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:51:55 2010''

Latest revision as of 13:18, 21 February 2024

Saccharomyces cerevisiae Cet1-Ceg1 capping apparatusSaccharomyces cerevisiae Cet1-Ceg1 capping apparatus

Structural highlights

3kyh is a 4 chain structure with sequence from Saccharomyces cerevisiae. The January 2012 RCSB PDB Molecule of the Month feature on Messenger RNA Capping by David Goodsell is 10.2210/rcsb_pdb/mom_2012_1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CET1_YEAST First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Hausmann S, Pei Y, Shuman S. Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases. J Biol Chem. 2003 Aug 15;278(33):30487-96. Epub 2003 Jun 3. PMID:12788946 doi:http://dx.doi.org/10.1074/jbc.M303060200

3kyh, resolution 3.00Å

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