3k4y: Difference between revisions

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-{{STRUCTURE_3k4y|  PDB=3k4y  |  SCENE=  }}
-===Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IPP===
-{{ABSTRACT_PUBMED_20392112}}
-==About this Structure==
+==Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IPP==
-[[3k4y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4Y OCA].
+<StructureSection load='3k4y' size='340' side='right'caption='[[3k4y]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
+== Structural highlights ==
-==Reference==
+<table><tr><td colspan='2'>[[3k4y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K4Y FirstGlance]. <br>
-<ref group="xtra">PMID:020392112</ref><references group="xtra"/><references/>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54&#8491;</td></tr>
-[[Category: Methanocaldococcus jannaschii]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Dellas, N.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4y OCA], [https://pdbe.org/3k4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k4y RCSB], [https://www.ebi.ac.uk/pdbsum/3k4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k4y ProSAT]</span></td></tr>
-[[Category: Noel, J P.]]
+</table>
-[[Category: Archaea]]
+== Function ==
-[[Category: Atp-binding]]
+[https://www.uniprot.org/uniprot/IPK_METJA IPK_METJA] Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.<ref>PMID:16621811</ref> <ref>PMID:20392112</ref>
-[[Category: Isopentenyl diphosphate]]
+== Evolutionary Conservation ==
-[[Category: Isopentenyl monophosphate]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Isoprenoid biosynthesis]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/3k4y_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k4y ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Methanocaldococcus jannaschii]]
-[[Category: Mevalonate pathway]]
+[[Category: Dellas N]]
-[[Category: Small molecule kinase]]
+[[Category: Noel JP]]
-[[Category: Transferase]]