3jr6: Difference between revisions

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-[[Image:3jr6.png|left|200px]]
-<!--
+==Sequential reorganization of beta-sheet topology by insertion of a single strand==
-The line below this paragraph, containing "STRUCTURE_3jr6", creates the "Structure Box" on the page.
+<StructureSection load='3jr6' size='340' side='right'caption='[[3jr6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3jr6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2b7w 2b7w]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JR6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_3jr6|  PDB=3jr6  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jr6 OCA], [https://pdbe.org/3jr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jr6 RCSB], [https://www.ebi.ac.uk/pdbsum/3jr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jr6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/3jr6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jr6 ConSurf].
+<div style="clear:both"></div>
-===Sequential reorganization of beta-sheet topology by insertion of a single strand===
+==See Also==
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_16597830}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 16597830 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Escherichia virus T4]]
-{{ABSTRACT_PUBMED_16597830}}
+[[Category: Large Structures]]
+[[Category: Baas WA]]
-==About this Structure==
+[[Category: Matthews BW]]
-[[3jr6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2b7w 2b7w]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JR6 OCA].
+[[Category: Sagermann M]]
-==Reference==
-<ref group="xtra">PMID:16597830</ref><ref group="xtra">PMID:12869697</ref><ref group="xtra">PMID:10339544</ref><references group="xtra"/>
-[[Category: Enterobacteria phage t4]]
-[[Category: Lysozyme]]
-[[Category: Baas, W A.]]
-[[Category: Matthews, B W.]]
-[[Category: Sagermann, M.]]
-[[Category: Antimicrobial]]
-[[Category: Bacteriolytic enzyme]]
-[[Category: Beta-sheet]]
-[[Category: Glycosidase]]
-[[Category: Hydrolase]]
-[[Category: Protein design]]
-[[Category: Sequence duplication]]
-[[Category: Tandem repeat]]