3j4r: Difference between revisions
New page: '''Unreleased structure''' The entry 3j4r is ON HOLD Authors: Reichow, S.L., Gonen, T., ,, ,, ,, ,, , Description: Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformatio... |
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==Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron microscopy== | |||
<SX load='3j4r' size='340' side='right' viewer='molstar' caption='[[3j4r]], [[Resolution|resolution]] 35.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3j4r]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J4R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J4R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 35Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j4r OCA], [https://pdbe.org/3j4r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j4r RCSB], [https://www.ebi.ac.uk/pdbsum/3j4r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j4r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AKA7G_RAT AKA7G_RAT] Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity). Isoform Delta may be involved in shuttling aquaporin-2 (AQP2) to the plasma membrane.[UniProtKB:Q9P0M2]<ref>PMID:15037626</ref> | |||
==See Also== | |||
*[[A-kinase anchor protein 3D structures|A-kinase anchor protein 3D structures]] | |||
*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Gonen T]] | |||
[[Category: Reichow SL]] |