3j16: Difference between revisions

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-'''Unreleased structure'''
-The entry 3j16 is ON HOLD
+==Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners==
+<SX load='3j16' size='340' side='right' viewer='molstar' caption='[[3j16]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3j16]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J16 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j16 OCA], [https://pdbe.org/3j16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j16 RCSB], [https://www.ebi.ac.uk/pdbsum/3j16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j16 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DOM34_YEAST DOM34_YEAST] Involved in protein translation. Together with HBS1, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. The complex formed by DOM34 and HBS1 has ribonuclease activity towards double-stranded RNA substrates, but does not cleave single-stranded RNA. Acts as endonuclease; has no exonuclease activity. Increases the affinity of HBS1 for GTP, but nor for GDP. Promotes G1 progression and differentiation and is involved in mitotic and meiotic cell divisions.<ref>PMID:16554824</ref> <ref>PMID:17889667</ref> <ref>PMID:18180287</ref>
-Authors: Becker, T., Franckenberg, S., Wickles, S., Shoemaker, C.J., Anger, A.M., Armache, J.-P., Sieber, H., Ungewickell, C., Berninghausen, O., Daberkow, I., Karcher, A., Thomm, M., Hopfner, K.-P., Green, R., Beckmann, R.
+==See Also==
+*[[Ribosomal protein S6|Ribosomal protein S6]]
-Description: Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners
+*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
+== References ==
+<references/>
+__TOC__
+</SX>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Anger AM]]
+[[Category: Armache J-P]]
+[[Category: Becker T]]
+[[Category: Beckmann R]]
+[[Category: Berninghausen O]]
+[[Category: Daberkow I]]
+[[Category: Franckenberg S]]
+[[Category: Green R]]
+[[Category: Hopfner K-P]]
+[[Category: Karcher A]]
+[[Category: Shoemaker CJ]]
+[[Category: Sieber H]]
+[[Category: Thomm M]]
+[[Category: Ungewickell C]]
+[[Category: Wickles S]]