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<SX load='3j0h' size='340' side='right' viewer='molstar' caption='[[3j0h]], [[Resolution|resolution]] 18.00&Aring;' scene=''>
<SX load='3j0h' size='340' side='right' viewer='molstar' caption='[[3j0h]], [[Resolution|resolution]] 18.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3j0h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_phikz Pseudomonas phage phikz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0H FirstGlance]. <br>
<table><tr><td colspan='2'>[[3j0h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phiKZ Pseudomonas virus phiKZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0H FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3spe|3spe]], [[3j0i|3j0i]], [[3hxl|3hxl]], [[3lml|3lml]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 18&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0h OCA], [https://pdbe.org/3j0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0h RCSB], [https://www.ebi.ac.uk/pdbsum/3j0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0h OCA], [https://pdbe.org/3j0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0h RCSB], [https://www.ebi.ac.uk/pdbsum/3j0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0h ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/Q8SDD3_BPDPK Q8SDD3_BPDPK]
Bacteriophage phiKZ is a giant phage that infects Pseudomonas aeruginosa, a human pathogen. The phiKZ virion consists of a 1450 A diameter icosahedral head and a 2000 A-long contractile tail. The structure of the whole virus was previously reported, showing that its tail organization in the extended state is similar to the well-studied Myovirus bacteriophage T4 tail. The crystal structure of a tail sheath protein fragment of phiKZ was determined to 2.4 A resolution. Furthermore, crystal structures of two prophage tail sheath proteins were determined to 1.9 and 3.3 A resolution. Despite low sequence identity between these proteins, all of these structures have a similar fold. The crystal structure of the phiKZ tail sheath protein has been fitted into cryo-electron-microscopy reconstructions of the extended tail sheath and of a polysheath. The structural rearrangement of the phiKZ tail sheath contraction was found to be similar to that of phage T4.
 
Structural conservation of the myoviridae phage tail sheath protein fold.,Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, Rossmann MG Structure. 2011 Dec 7;19(12):1885-94. PMID:22153511<ref>PMID:22153511</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3j0h" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</SX>
</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseudomonas phage phikz]]
[[Category: Pseudomonas virus phiKZ]]
[[Category: Aksyuk, A A]]
[[Category: Aksyuk AA]]
[[Category: Fokine, A]]
[[Category: Fokine A]]
[[Category: Kurochkina, L P]]
[[Category: Kurochkina LP]]
[[Category: Mesyanzhinov, V V]]
[[Category: Mesyanzhinov VV]]
[[Category: Rossmann, M G]]
[[Category: Rossmann MG]]
[[Category: Structural protein]]

Latest revision as of 13:09, 21 February 2024

Fitting of the bacteriophage phiKZ gp29PR structure into the cryo-EM density map of the phiKZ extended tail sheathFitting of the bacteriophage phiKZ gp29PR structure into the cryo-EM density map of the phiKZ extended tail sheath

3j0h, resolution 18.00Å

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