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| ==Fitting of the bacteriophage phiKZ gp29PR structure into the cryo-EM density map of the phiKZ extended tail sheath== | | ==Fitting of the bacteriophage phiKZ gp29PR structure into the cryo-EM density map of the phiKZ extended tail sheath== |
| <StructureSection load='3j0h' size='340' side='right' caption='[[3j0h]], [[Resolution|resolution]] 18.00Å' scene=''> | | <SX load='3j0h' size='340' side='right' viewer='molstar' caption='[[3j0h]], [[Resolution|resolution]] 18.00Å' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[3j0h]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpdpk Bpdpk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J0H FirstGlance]. <br> | | <table><tr><td colspan='2'>[[3j0h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phiKZ Pseudomonas virus phiKZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0H FirstGlance]. <br> |
| </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3spe|3spe]], [[3j0i|3j0i]], [[3hxl|3hxl]], [[3lml|3lml]]</td></tr> | | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 18Å</td></tr> |
| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j0h RCSB], [http://www.ebi.ac.uk/pdbsum/3j0h PDBsum]</span></td></tr> | | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0h OCA], [https://pdbe.org/3j0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0h RCSB], [https://www.ebi.ac.uk/pdbsum/3j0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0h ProSAT]</span></td></tr> |
| </table> | | </table> |
| <div style="background-color:#fffaf0;">
| | == Function == |
| == Publication Abstract from PubMed == | | [https://www.uniprot.org/uniprot/Q8SDD3_BPDPK Q8SDD3_BPDPK] |
| Bacteriophage phiKZ is a giant phage that infects Pseudomonas aeruginosa, a human pathogen. The phiKZ virion consists of a 1450 A diameter icosahedral head and a 2000 A-long contractile tail. The structure of the whole virus was previously reported, showing that its tail organization in the extended state is similar to the well-studied Myovirus bacteriophage T4 tail. The crystal structure of a tail sheath protein fragment of phiKZ was determined to 2.4 A resolution. Furthermore, crystal structures of two prophage tail sheath proteins were determined to 1.9 and 3.3 A resolution. Despite low sequence identity between these proteins, all of these structures have a similar fold. The crystal structure of the phiKZ tail sheath protein has been fitted into cryo-electron-microscopy reconstructions of the extended tail sheath and of a polysheath. The structural rearrangement of the phiKZ tail sheath contraction was found to be similar to that of phage T4.
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| Structural conservation of the myoviridae phage tail sheath protein fold.,Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, Rossmann MG Structure. 2011 Dec 7;19(12):1885-94. PMID:22153511<ref>PMID:22153511</ref>
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| From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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| </div>
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| == References ==
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| <references/>
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| __TOC__ | | __TOC__ |
| </StructureSection> | | </SX> |
| [[Category: Bpdpk]] | | [[Category: Large Structures]] |
| [[Category: Aksyuk, A A]] | | [[Category: Pseudomonas virus phiKZ]] |
| [[Category: Fokine, A]] | | [[Category: Aksyuk AA]] |
| [[Category: Kurochkina, L P]] | | [[Category: Fokine A]] |
| [[Category: Mesyanzhinov, V V]] | | [[Category: Kurochkina LP]] |
| [[Category: Rossmann, M G]] | | [[Category: Mesyanzhinov VV]] |
| [[Category: Structural protein]] | | [[Category: Rossmann MG]] |