3iyv: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 ==Clathrin D6 coat as full-length Triskelions==
-<StructureSection load='3iyv' size='340' side='right' caption='[[3iyv]], [[Resolution|resolution]] 7.90&Aring;' scene=''>
+<SX load='3iyv' size='340' side='right' viewer='molstar' caption='[[3iyv]], [[Resolution|resolution]] 7.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3iyv]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3iyv]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYV FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xi4|1xi4]], [[1xi5|1xi5]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.9&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyv OCA], [http://pdbe.org/3iyv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyv RCSB], [http://www.ebi.ac.uk/pdbsum/3iyv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyv ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyv OCA], [https://pdbe.org/3iyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyv RCSB], [https://www.ebi.ac.uk/pdbsum/3iyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyv ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CLH1_BOVIN CLH1_BOVIN]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. [[http://www.uniprot.org/uniprot/CLCA_BOVIN CLCA_BOVIN]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
+[https://www.uniprot.org/uniprot/CLH1_BOVIN CLH1_BOVIN] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iyv_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iyv_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 19: / Line 19: @@
 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iyv ConSurf].
 <div style="clear:both"></div>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-Clathrin-coated vesicles are important vehicles of membrane traffic in cells. We report the structure of a clathrin lattice at subnanometre resolution, obtained from electron cryomicroscopy of coats assembled in vitro. We trace most of the 1,675-residue clathrin heavy chain by fitting known crystal structures of two segments, and homology models of the rest, into the electron microscopy density map. We also define the position of the central helical segment of the light chain. A helical tripod, the carboxy-terminal parts of three heavy chains, projects inward from the vertex of each three-legged clathrin triskelion, linking that vertex to 'ankles' of triskelions centred two vertices away. Analysis of coats with distinct diameters shows an invariant pattern of contacts in the neighbourhood of each vertex, with more variable interactions along the extended parts of the triskelion 'legs'. These invariant local interactions appear to stabilize the lattice, allowing assembly and uncoating to be controlled by events at a few specific sites.
-Molecular model for a complete clathrin lattice from electron cryomicroscopy.,Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T Nature. 2004 Dec 2;432(7017):573-9. Epub 2004 Oct 24. PMID:15502812<ref>PMID:15502812</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 3iyv" style="background-color:#fffaf0;"></div>
 ==See Also==
 *[[Clathrin|Clathrin]]
-== References ==
+*[[Clathrin 3D structures|Clathrin 3D structures]]
-<references/>
 __TOC__
-</StructureSection>
+</SX>
 [[Category: Bos taurus]]
-[[Category: Cheng, Y]]
+[[Category: Large Structures]]
-[[Category: Fotin, A]]
+[[Category: Cheng Y]]
-[[Category: Grigorieff, N]]
+[[Category: Fotin A]]
-[[Category: Harrison, S C]]
+[[Category: Grigorieff N]]
-[[Category: Johnson, G T]]
+[[Category: Harrison SC]]
-[[Category: Kirchhausen, T]]
+[[Category: Johnson GT]]
-[[Category: Sliz, P]]
+[[Category: Kirchhausen T]]
-[[Category: Walz, T]]
+[[Category: Sliz P]]
-[[Category: Alpha-zig-zag]]
+[[Category: Walz T]]
-[[Category: Beta-propeller]]
-[[Category: Clathrin]]
-[[Category: Endocytosis-exocytosis complex]]