3ix6: Difference between revisions

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[[Image:3ix6.jpg|left|200px]]


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==Crystal structure of Thymidylate synthase thyA from Brucella melitensis==
The line below this paragraph, containing "STRUCTURE_3ix6", creates the "Structure Box" on the page.
<StructureSection load='3ix6' size='340' side='right'caption='[[3ix6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ix6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_melitensis Brucella melitensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IX6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ix6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ix6 OCA], [https://pdbe.org/3ix6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ix6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ix6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ix6 ProSAT]</span></td></tr>
{{STRUCTURE_3ix6| PDB=3ix6 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYSY_BRUME TYSY_BRUME] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ix6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ix6 ConSurf].
<div style="clear:both"></div>


===Crystal structure of Thymidylate synthase thyA from Brucella melitensis===
==See Also==
 
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3IX6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Brucella_melitensis Brucella melitensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IX6 OCA].
[[Category: Brucella melitensis]]
[[Category: Brucella melitensis]]
[[Category: Thymidylate synthase]]
[[Category: Large Structures]]
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
[[Category: Brucellosis]]
[[Category: Cytoplasm]]
[[Category: Epididymitis]]
[[Category: Mastitis]]
[[Category: Methyltransferase]]
[[Category: Niaid]]
[[Category: Nucleotide biosynthesis]]
[[Category: Orchitis]]
[[Category: Seattle structural center for infectious disease]]
[[Category: Seattle structural genomics center for infectious disease]]
[[Category: Ssgcid]]
[[Category: Structural genomic]]
[[Category: Thymidylate]]
[[Category: Transferase]]
 
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