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[[Image:3hid.png|left|200px]]


{{STRUCTURE_3hid|  PDB=3hid  |  SCENE=  }}
==Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92==
 
<StructureSection load='3hid' size='340' side='right'caption='[[3hid]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3hid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HID FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG6:1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE'>PG6</scene></td></tr>
[[3hid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HID OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hid OCA], [https://pdbe.org/3hid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hid RCSB], [https://www.ebi.ac.uk/pdbsum/3hid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hid ProSAT], [https://www.topsan.org/Proteins/CSGID/3hid TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PURA_YERPE PURA_YERPE] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3hid_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hid ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Adenylosuccinate Synthetase|Adenylosuccinate Synthetase]]
*[[Adenylosuccinate Synthetase|Adenylosuccinate Synthetase]]
[[Category: Adenylosuccinate synthase]]
*[[Adenylosuccinate synthetase 3D structures|Adenylosuccinate synthetase 3D structures]]
[[Category: Yersinia pestis co92]]
__TOC__
[[Category: Anderson, W.]]
</StructureSection>
[[Category: Joachimiak, A.]]
[[Category: Large Structures]]
[[Category: Peterson, S.]]
[[Category: Yersinia pestis CO92]]
[[Category: Zhang, R.]]
[[Category: Anderson W]]
[[Category: Zhou, M.]]
[[Category: Joachimiak A]]
[[Category: Adenylosuccinate synthetase]]
[[Category: Peterson S]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Zhang R]]
[[Category: Csgid]]
[[Category: Zhou M]]
[[Category: Gtp-binding]]
[[Category: Ligase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Niaid structural genomic]]
[[Category: Nucleotide-binding]]
[[Category: Pura]]
[[Category: Purine biosynthesis]]
[[Category: Purine ribonucleotide biosynthesis]]
[[Category: Virulence associated factor]]

Latest revision as of 13:00, 21 February 2024

Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92

Structural highlights

3hid is a 1 chain structure with sequence from Yersinia pestis CO92. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PURA_YERPE Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3hid, resolution 1.60Å

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