3hfb: Difference between revisions

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OCA

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-[[Image:3hfb.png|left|200px]]
-<!--
+==Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193==
-The line below this paragraph, containing "STRUCTURE_3hfb", creates the "Structure Box" on the page.
+<StructureSection load='3hfb' size='340' side='right'caption='[[3hfb]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3hfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFB FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ML4:4-(5-{[(2-METHYLBIPHENYL-2-YL)METHYL]AMINO}PYRAZIN-2-YL)-L-PHENYLALANINE'>ML4</scene></td></tr>
-{{STRUCTURE_3hfb|  PDB=3hfb  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfb OCA], [https://pdbe.org/3hfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfb RCSB], [https://www.ebi.ac.uk/pdbsum/3hfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfb ProSAT]</span></td></tr>
+</table>
-===Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193===
+== Function ==
+[https://www.uniprot.org/uniprot/TPH1_HUMAN TPH1_HUMAN]
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-[[3hfb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA].
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hfb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hfb ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Tryptophan hydroxylase]]
+*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Tryptophan 5-monooxygenase]]
+[[Category: Large Structures]]
-[[Category: Hunter, M J.]]
+[[Category: Hunter MJ]]
-[[Category: Swanson, R V.]]
+[[Category: Swanson RV]]
-[[Category: Tari, L W.]]
+[[Category: Tari LW]]
-[[Category: Alternative splicing]]
-[[Category: Iron]]
-[[Category: Metal-binding]]
-[[Category: Monooxygenase]]
-[[Category: Oxidoreductase]]
-[[Category: Phosphoprotein]]
-[[Category: Serotonin biosynthesis]]
-[[Category: Tryptophan hydroxylase type 1]]