3hfb: Difference between revisions

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==Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193==
The line below this paragraph, containing "STRUCTURE_3hfb", creates the "Structure Box" on the page.
<StructureSection load='3hfb' size='340' side='right'caption='[[3hfb]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3hfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ML4:4-(5-{[(2-METHYLBIPHENYL-2-YL)METHYL]AMINO}PYRAZIN-2-YL)-L-PHENYLALANINE'>ML4</scene></td></tr>
{{STRUCTURE_3hfb| PDB=3hfb |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfb OCA], [https://pdbe.org/3hfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfb RCSB], [https://www.ebi.ac.uk/pdbsum/3hfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPH1_HUMAN TPH1_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hfb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hfb ConSurf].
<div style="clear:both"></div>


===Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193===
==See Also==
 
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3HFB is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFB OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Tryptophan 5-monooxygenase]]
[[Category: Large Structures]]
[[Category: Hunter, M J.]]
[[Category: Hunter MJ]]
[[Category: Swanson, R V.]]
[[Category: Swanson RV]]
[[Category: Tari, L W.]]
[[Category: Tari LW]]
[[Category: Alternative splicing]]
[[Category: Iron]]
[[Category: Metal-binding]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]
[[Category: Phosphoprotein]]
[[Category: Serotonin biosynthesis]]
[[Category: Tryptophan hydroxylase type 1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 27 10:27:50 2010''

Latest revision as of 12:59, 21 February 2024

Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193

Structural highlights

3hfb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.92Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TPH1_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3hfb, resolution 1.92Å

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