3gd8: Difference between revisions

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-{{Seed}}
-[[Image:3gd8.png|left|200px]]
-<!--
+==Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance==
-The line below this paragraph, containing "STRUCTURE_3gd8", creates the "Structure Box" on the page.
+<StructureSection load='3gd8' size='340' side='right'caption='[[3gd8]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3gd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GD8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-{{STRUCTURE_3gd8|  PDB=3gd8  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gd8 OCA], [https://pdbe.org/3gd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gd8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gd8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/AQP4_HUMAN AQP4_HUMAN] Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/3gd8_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gd8 ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance===
+==See Also==
+*[[Aquaporin 3D structures|Aquaporin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_19383790}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 19383790 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_19383790}}
-==About this Structure==
-GD8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GD8 OCA].
-==Reference==
-<ref group="xtra">PMID:19383790</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: CSMP, Center for Structures of Membrane Proteins.]]
+[[Category: Large Structures]]
-[[Category: Chorny, I.]]
+[[Category: Chorny I]]
-[[Category: Harries, W E.C.]]
+[[Category: Harries WEC]]
-[[Category: Ho, J D.]]
+[[Category: Ho JD]]
-[[Category: Miercke, L J.W.]]
+[[Category: Miercke LJW]]
-[[Category: Robbins, R A.]]
+[[Category: Robbins RA]]
-[[Category: Sandstrom, A.]]
+[[Category: Sandstrom A]]
-[[Category: Stroud, R M.]]
+[[Category: Stroud RM]]
-[[Category: Yeh, R.]]
+[[Category: Yeh R]]
-[[Category: Alternative splicing]]
-[[Category: Aquaporin]]
-[[Category: Brain edema]]
-[[Category: Center for structures of membrane protein]]
-[[Category: Csmp]]
-[[Category: Glycoprotein]]
-[[Category: Membrane]]
-[[Category: Phosphoprotein]]
-[[Category: Protein structure initiative]]
-[[Category: Proton exclusion]]
-[[Category: Psi-2]]
-[[Category: Structural genomic]]
-[[Category: Transmembrane]]
-[[Category: Transport]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:51:30 2009''