3g8c: Difference between revisions

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[[Image:3g8c.jpg|left|200px]]


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==Crystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion==
The line below this paragraph, containing "STRUCTURE_3g8c", creates the "Structure Box" on the page.
<StructureSection load='3g8c' size='340' side='right'caption='[[3g8c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3g8c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G8C FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3g8c| PDB=3g8c |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g8c OCA], [https://pdbe.org/3g8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g8c RCSB], [https://www.ebi.ac.uk/pdbsum/3g8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g8c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/3g8c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g8c ConSurf].
<div style="clear:both"></div>


===Crystal Stucture of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion===
==See Also==
 
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
(as it appears on PubMed at http://www.pubmed.gov), where 19213731 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Chou CY]]
{{ABSTRACT_PUBMED_19213731}}
[[Category: Tong L]]
 
[[Category: Yu LP]]
==About this Structure==
3G8C is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8C OCA].
 
==Reference==
<ref group="xtra">PMID:19213731</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Chou, C Y.]]
[[Category: Tong, L.]]
[[Category: Yu, L P.]]
[[Category: Atp-binding]]
[[Category: Atp-grasp]]
[[Category: Biotin]]
[[Category: Biotin-dependent]]
[[Category: Carboxylase]]
[[Category: Fatty acid biosynthesis]]
[[Category: Fatty acid synthesis]]
[[Category: Ligase]]
[[Category: Lipid synthesis]]
[[Category: Nucleotide-binding]]
[[Category: Substrates bound]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  4 15:01:43 2009''

Latest revision as of 12:52, 21 February 2024

Crystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg IonCrystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion

Structural highlights

3g8c is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACCC_ECOLI This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3g8c, resolution 2.00Å

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