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{{Seed}}
[[Image:3fwb.png|left|200px]]


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==Sac3:Sus1:Cdc31 complex==
The line below this paragraph, containing "STRUCTURE_3fwb", creates the "Structure Box" on the page.
<StructureSection load='3fwb' size='340' side='right'caption='[[3fwb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3fwb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwb OCA], [https://pdbe.org/3fwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwb RCSB], [https://www.ebi.ac.uk/pdbsum/3fwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwb ProSAT]</span></td></tr>
{{STRUCTURE_3fwb| PDB=3fwb |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDC31_YEAST CDC31_YEAST] Functions as a component of the nuclear pore complex (NPC) and the spindle pole body (SPB) half-bridge. At the SPB, it is recruited by KAR1 and MPS3 to the SPB half-bridge and involved in the initial steps of SPB duplication. It probably plays a similar role in de novo assembly of NPCs at the nuclear envelope. Also involved in connection with the protein kinase KIC1 in the maintenance of cell morphology and integrity.<ref>PMID:8188750</ref> <ref>PMID:8070654</ref> <ref>PMID:9813095</ref> <ref>PMID:11156974</ref> <ref>PMID:12486115</ref> <ref>PMID:14504268</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwb ConSurf].
<div style="clear:both"></div>


===Sac3:Sus1:Cdc31 complex===
==See Also==
 
*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 19328066 is the PubMed ID number.
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_19328066}}
 
==About this Structure==
3FWB is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWB OCA].
 
==Reference==
<ref group="xtra">PMID:19328066</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Jani, D.]]
[[Category: Jani D]]
[[Category: Stewart, M.]]
[[Category: Stewart M]]
[[Category: Acetylation]]
[[Category: Calcium]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Complex]]
[[Category: Gene gating]]
[[Category: Mitosis]]
[[Category: Mrna transport]]
[[Category: Nuclear pore complex]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein transport]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Translocation]]
[[Category: Transport]]
 
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