3fqv: Difference between revisions

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-{{Seed}}
-[[Image:3fqv.jpg|left|200px]]
-<!--
+==Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine==
-The line below this paragraph, containing "STRUCTURE_3fqv", creates the "Structure Box" on the page.
+<StructureSection load='3fqv' size='340' side='right'caption='[[3fqv]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3fqv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_RF122 Staphylococcus aureus RF122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FQV FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=11F:5-[(3S)-3-(2-METHOXYBIPHENYL-4-YL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2,4-DIAMINE'>11F</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-{{STRUCTURE_3fqv|  PDB=3fqv  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fqv OCA], [https://pdbe.org/3fqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fqv RCSB], [https://www.ebi.ac.uk/pdbsum/3fqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fqv ProSAT]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/3fqv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fqv ConSurf].
+<div style="clear:both"></div>
-===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine===
+==See Also==
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_19249312}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 19249312 is the PubMed ID number.
+[[Category: Staphylococcus aureus RF122]]
--->
+[[Category: Anderson AC]]
-{{ABSTRACT_PUBMED_19249312}}
+[[Category: Frey KM]]
+[[Category: Liu J]]
-==About this Structure==
+[[Category: Lombardo MN]]
-FQV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQV OCA].
-==Reference==
-<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
-[[Category: Dihydrofolate reductase]]
-[[Category: Staphylococcus aureus rf122]]
-[[Category: Anderson, A C.]]
-[[Category: Frey, K M.]]
-[[Category: Liu, J.]]
-[[Category: Lombardo, M N.]]
-[[Category: Oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:33:15 2009''