3eej: Difference between revisions

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-[[Image:3eej.png|left|200px]]
-{{STRUCTURE_3eej|  PDB=3eej  |  SCENE=  }}
+==Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D) and NADPH==
+<StructureSection load='3eej' size='340' side='right'caption='[[3eej]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
-===Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D) and NADPH===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3eej]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EEJ FirstGlance]. <br>
-{{ABSTRACT_PUBMED_19152636}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=53R:5-[(3R)-3-(5-METHOXYBIPHENYL-3-YL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2,4-DIAMINE'>53R</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eej OCA], [https://pdbe.org/3eej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eej RCSB], [https://www.ebi.ac.uk/pdbsum/3eej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eej ProSAT]</span></td></tr>
-[[3eej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EEJ OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q6FPH0_CANGA Q6FPH0_CANGA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/3eej_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eej ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Dihydrofolate reductase|Dihydrofolate reductase]]
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:019152636</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Candida glabrata]]
+[[Category: Anderson A]]
-[[Category: Anderson, A.]]
+[[Category: Liu J]]
-[[Category: Liu, J.]]
-[[Category: Enzyme]]
-[[Category: Oxidoreductase]]