3dyh: Difference between revisions

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-[[Image:3dyh.png|left|200px]]
-{{STRUCTURE_3dyh|  PDB=3dyh  |  SCENE=  }}
+==T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-721==
+<StructureSection load='3dyh' size='340' side='right'caption='[[3dyh]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
-===T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-721===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3dyh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DYH FirstGlance]. <br>
-{{ABSTRACT_PUBMED_19309137}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=721:3-BUTOXY-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM'>721</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dyh OCA], [https://pdbe.org/3dyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dyh RCSB], [https://www.ebi.ac.uk/pdbsum/3dyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dyh ProSAT]</span></td></tr>
-[[3dyh]] is a 2 chain structure of [[Farnesyl diphosphate synthase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYH OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q86C09_9TRYP Q86C09_9TRYP]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/3dyh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dyh ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
+*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:019309137</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Geranyltranstransferase]]
 [[Category: Trypanosoma brucei]]
-[[Category: Cao, R.]]
+[[Category: Cao R]]
-[[Category: Gao, Y.]]
+[[Category: Gao Y]]
-[[Category: Goddard, A.]]
+[[Category: Goddard A]]
-[[Category: Oldfield, E.]]
+[[Category: Oldfield E]]
-[[Category: Robinson, H.]]
+[[Category: Robinson H]]
-[[Category: Isoprene biosynthesis]]
-[[Category: Protein-bisphosphonate complex]]
-[[Category: Transferase]]