3dra: Difference between revisions

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-{{Seed}}
-[[Image:3dra.jpg|left|200px]]
-<!--
+==Candida albicans protein geranylgeranyltransferase-I complexed with GGPP==
-The line below this paragraph, containing "STRUCTURE_3dra", creates the "Structure Box" on the page.
+<StructureSection load='3dra' size='340' side='right'caption='[[3dra]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3dra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRA FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_3dra|  PDB=3dra  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dra OCA], [https://pdbe.org/3dra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dra RCSB], [https://www.ebi.ac.uk/pdbsum/3dra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dra ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FNTA_CANAX FNTA_CANAX] Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dra_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dra ConSurf].
+<div style="clear:both"></div>
-===Candida albicans protein geranylgeranyltransferase-I complexed with GGPP===
+==See Also==
+*[[Geranylgeranyl transferase 3D structures|Geranylgeranyl transferase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_18713740}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 18713740 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_18713740}}
-==About this Structure==
-DRA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRA OCA].
-==Reference==
-Structure of protein geranylgeranyltransferase-I from the human pathogen Candida albicans complexed with a lipid substrate., Hast MA, Beese LS, J Biol Chem. 2008 Aug 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18713740 18713740]
 [[Category: Candida albicans]]
-[[Category: Protein complex]]
+[[Category: Large Structures]]
-[[Category: Beese, L S.]]
+[[Category: Beese LS]]
-[[Category: Hast, M A.]]
+[[Category: Hast MA]]
-[[Category: Candida]]
-[[Category: Candida albican]]
-[[Category: Farnesyltransferase]]
-[[Category: Geranylgeranyl diphosphate]]
-[[Category: Geranylgeranylpyrophosphate]]
-[[Category: Geranylgeranyltransferase type-i]]
-[[Category: Geranylgeranyltrasferase]]
-[[Category: Ggpp]]
-[[Category: Ggtase]]
-[[Category: Ggtase-i]]
-[[Category: Pggt]]
-[[Category: Prenylation]]
-[[Category: Prenyltransferase]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  1 21:44:17 2008''