3dra: Difference between revisions
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New page: '''Unreleased structure''' The entry 3dra is ON HOLD Authors: Hast, M.A., Beese, L.S. Description: Candida albicans protein geranylgeranyltransferase-I complexed with GGPP ''Page seed... |
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==Candida albicans protein geranylgeranyltransferase-I complexed with GGPP== | |||
<StructureSection load='3dra' size='340' side='right'caption='[[3dra]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3dra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dra OCA], [https://pdbe.org/3dra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dra RCSB], [https://www.ebi.ac.uk/pdbsum/3dra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dra ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FNTA_CANAX FNTA_CANAX] Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dra_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dra ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Geranylgeranyl transferase 3D structures|Geranylgeranyl transferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Candida albicans]] | |||
[[Category: Large Structures]] | |||
[[Category: Beese LS]] | |||
[[Category: Hast MA]] | |||
Latest revision as of 12:42, 21 February 2024
Candida albicans protein geranylgeranyltransferase-I complexed with GGPPCandida albicans protein geranylgeranyltransferase-I complexed with GGPP
Structural highlights
FunctionFNTA_CANAX Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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