3dkn: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:3dkn.jpg|left|200px]]


<!--
==Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulum==
The line below this paragraph, containing "STRUCTURE_3dkn", creates the "Structure Box" on the page.
<SX load='3dkn' size='340' side='right' viewer='molstar' caption='[[3dkn]], [[Resolution|resolution]] 8.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3dkn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DKN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.7&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dkn OCA], [https://pdbe.org/3dkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dkn RCSB], [https://www.ebi.ac.uk/pdbsum/3dkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dkn ProSAT]</span></td></tr>
{{STRUCTURE_3dkn| PDB=3dkn |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/3dkn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dkn ConSurf].
<div style="clear:both"></div>


===Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulum===
==See Also==
 
*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
 
__TOC__
<!--
</SX>
The line below this paragraph, {{ABSTRACT_PUBMED_18611385}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 18611385 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_18611385}}
 
==About this Structure==
3DKN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKN OCA].
 
==Reference==
Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome., Menetret JF, Hegde RS, Aguiar M, Gygi SP, Park E, Rapoport TA, Akey CW, Structure. 2008 Jul;16(7):1126-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18611385 18611385]
[[Category: Canis lupus familiaris]]
[[Category: Canis lupus familiaris]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Akey, C.]]
[[Category: Akey C]]
[[Category: Menetret, J F.]]
[[Category: Menetret J-F]]
[[Category: Co-translational translocation]]
[[Category: Cryo-electron microscopy]]
[[Category: Endoplasmic reticulum]]
[[Category: Protein transport/rna complex]]
[[Category: Ribosome-channel complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 20 12:07:16 2008''

Latest revision as of 12:41, 21 February 2024

Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulumSec61 in the Canine ribosome-channel complex from the endoplasmic reticulum

3dkn, resolution 8.70Å

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3dkn&oldid=4064267"