3dkn: Difference between revisions

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-[[Image:3dkn.png|left|200px]]
-<!--
+==Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulum==
-The line below this paragraph, containing "STRUCTURE_3dkn", creates the "Structure Box" on the page.
+<SX load='3dkn' size='340' side='right' viewer='molstar' caption='[[3dkn]], [[Resolution|resolution]] 8.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3dkn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DKN FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.7&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dkn OCA], [https://pdbe.org/3dkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dkn RCSB], [https://www.ebi.ac.uk/pdbsum/3dkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dkn ProSAT]</span></td></tr>
-{{STRUCTURE_3dkn|  PDB=3dkn  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/3dkn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dkn ConSurf].
+<div style="clear:both"></div>
-===Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulum===
+==See Also==
+*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
+__TOC__
-<!--
+</SX>
-The line below this paragraph, {{ABSTRACT_PUBMED_18611385}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 18611385 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_18611385}}
-==About this Structure==
-[[3dkn]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKN OCA].
-==Reference==
-<ref group="xtra">PMID:018611385</ref><references group="xtra"/>
 [[Category: Canis lupus familiaris]]
-[[Category: Akey, C.]]
+[[Category: Large Structures]]
-[[Category: Menetret, J F.]]
+[[Category: Akey C]]
-[[Category: Co-translational translocation]]
+[[Category: Menetret J-F]]
-[[Category: Endoplasmic reticulum]]
-[[Category: Protein transport-rna complex]]
-[[Category: Ribosome-channel complex]]