3dhh: Difference between revisions

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[[Image:3dhh.jpg|left|200px]]


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==Crystal Structure of Resting State Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein==
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<StructureSection load='3dhh' size='340' side='right'caption='[[3dhh]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3dhh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BML:4-BROMOPHENOL'>BML</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
{{STRUCTURE_3dhh| PDB=3dhh |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dhh OCA], [https://pdbe.org/3dhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dhh RCSB], [https://www.ebi.ac.uk/pdbsum/3dhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dhh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TMOE_PSEME TMOE_PSEME] Subunit of the multicomponent enzyme toluene-4-monooxygenase that hydroxylates toluene to form p-cresol.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/3dhh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dhh ConSurf].
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===Crystal Structure of Resting State Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein===
==See Also==
 
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
 
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</StructureSection>
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[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 19033467 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19033467}}
 
==About this Structure==
3DHH is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_mendocina Pseudomonas mendocina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHH OCA].
 
==Reference==
Structural consequences of effector protein complex formation in a diiron hydroxylase., Bailey LJ, McCoy JG, Phillips GN Jr, Fox BG, Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19194-8. Epub 2008 Nov 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19033467 19033467]
[[Category: Pseudomonas mendocina]]
[[Category: Pseudomonas mendocina]]
[[Category: Bailey, L J.]]
[[Category: Bailey LJ]]
[[Category: Fox, B G.]]
[[Category: Fox BG]]
[[Category: Mccoy, J G.]]
[[Category: Mccoy JG]]
[[Category: Phillips, G N.]]
[[Category: Phillips Jr GN]]
[[Category: Aromatic hydrocarbons catabolism]]
[[Category: Fad]]
[[Category: Flavoprotein]]
[[Category: Iron]]
[[Category: Monooxygenase]]
[[Category: Multicomponent monooxygenase]]
[[Category: Oxidoreductase]]
 
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