3dco: Difference between revisions

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-[[Image:3dco.png|left|200px]]
-{{STRUCTURE_3dco|  PDB=3dco  |  SCENE=  }}
+==Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule==
+<SX load='3dco' size='340' side='right' viewer='molstar' caption='[[3dco]], [[Resolution|resolution]] 11.00&Aring;' scene=''>
-===Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3dco]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DCO FirstGlance]. <br>
-{{ABSTRACT_PUBMED_19135893}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dco OCA], [https://pdbe.org/3dco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dco RCSB], [https://www.ebi.ac.uk/pdbsum/3dco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dco ProSAT]</span></td></tr>
-[[3dco]] is a 3 chain structure of [[Kinesin]] and [[Tubulin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCO OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NOD_DROME NOD_DROME] Required for the distributive chromosome segregation of non-exchange chromosomes during meiosis. May be a microtubule motor required to hold distributively "paired" chromosomes at the metaphase plate until anaphase.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/3dco_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dco ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Kinesin|Kinesin]]
+*[[Kinesin 3D Structures|Kinesin 3D Structures]]
-*[[Tubulin|Tubulin]]
+*[[Tubulin 3D Structures|Tubulin 3D Structures]]
+__TOC__
-==Reference==
+</SX>
-<ref group="xtra">PMID:019135893</ref><references group="xtra"/>
 [[Category: Bos taurus]]
 [[Category: Drosophila melanogaster]]
-[[Category: Cochran, J C.]]
+[[Category: Large Structures]]
-[[Category: Kull, F J.]]
+[[Category: Cochran JC]]
-[[Category: Sindelar, C V.]]
+[[Category: Kull FJ]]
-[[Category: 3d reconstruction]]
+[[Category: Sindelar CV]]
-[[Category: Adp]]
-[[Category: Atp-binding]]
-[[Category: Atpase]]
-[[Category: Catalytic domain]]
-[[Category: Cryo-em]]
-[[Category: Kinesin]]
-[[Category: Microtubule]]
-[[Category: Motor protein]]
-[[Category: Nucleotide-binding]]
-[[Category: Nucleotide-binding protein]]
-[[Category: Nucleotide-free]]
-[[Category: Tubulin]]