3dba: Difference between revisions

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-{{Seed}}
-[[Image:3dba.png|left|200px]]
-<!--
+==Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C==
-The line below this paragraph, containing "STRUCTURE_3dba", creates the "Structure Box" on the page.
+<StructureSection load='3dba' size='340' side='right'caption='[[3dba]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3dba]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBA FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35G:GUANOSINE-3,5-MONOPHOSPHATE'>35G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-{{STRUCTURE_3dba|  PDB=3dba  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dba OCA], [https://pdbe.org/3dba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dba RCSB], [https://www.ebi.ac.uk/pdbsum/3dba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dba ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PDE6C_CHICK PDE6C_CHICK]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3dba_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dba ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C===
+==See Also==
+*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_18614542}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 18614542 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_18614542}}
-==About this Structure==
-DBA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA].
-==Reference==
-The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change., Martinez SE, Heikaus CC, Klevit RE, Beavo JA, J Biol Chem. 2008 Sep 19;283(38):25913-9. Epub 2008 Jul 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18614542 18614542]
-[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
 [[Category: Gallus gallus]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Beavo, J A.]]
+[[Category: Beavo JA]]
-[[Category: Heikaus, C C.]]
+[[Category: Heikaus CC]]
-[[Category: Klevit, R E.]]
+[[Category: Klevit RE]]
-[[Category: Martinez, S E.]]
+[[Category: Martinez SE]]
-[[Category: 3s']]
-[[Category: 5' cgmp]]
-[[Category: Cgmp]]
-[[Category: Cyclic nucleotide phosphodiesterase]]
-[[Category: Gaf domain]]
-[[Category: Hydrolase]]
-[[Category: Lipoprotein]]
-[[Category: Membrane]]
-[[Category: Prenylation]]
-[[Category: Sensory transduction]]
-[[Category: Vision]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 24 09:17:41 2008''