3dba: Difference between revisions

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[[Image:3dba.png|left|200px]]


{{STRUCTURE_3dba|  PDB=3dba  |  SCENE=  }}
==Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C==
 
<StructureSection load='3dba' size='340' side='right'caption='[[3dba]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
===Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3dba]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBA FirstGlance]. <br>
{{ABSTRACT_PUBMED_18614542}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35G:GUANOSINE-3,5-MONOPHOSPHATE'>35G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dba OCA], [https://pdbe.org/3dba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dba RCSB], [https://www.ebi.ac.uk/pdbsum/3dba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dba ProSAT]</span></td></tr>
[[3dba]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDE6C_CHICK PDE6C_CHICK]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3dba_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dba ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphodiesterase|Phosphodiesterase]]
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:018614542</ref><ref group="xtra">PMID:020600113</ref><references group="xtra"/>
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Beavo, J A.]]
[[Category: Large Structures]]
[[Category: Heikaus, C C.]]
[[Category: Beavo JA]]
[[Category: Klevit, R E.]]
[[Category: Heikaus CC]]
[[Category: Martinez, S E.]]
[[Category: Klevit RE]]
[[Category: 3s']]
[[Category: Martinez SE]]
[[Category: 5' cgmp]]
[[Category: Cgmp]]
[[Category: Cyclic nucleotide phosphodiesterase]]
[[Category: Gaf domain]]
[[Category: Hydrolase]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Prenylation]]
[[Category: Sensory transduction]]
[[Category: Vision]]

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