3d3m: Difference between revisions

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-{{STRUCTURE_3d3m|  PDB=3d3m  |  SCENE=  }}
-===The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)===
-{{ABSTRACT_PUBMED_18722383}}
-==About this Structure==
+==The Crystal Structure of the C-terminal region of Death Associated Protein 5(DAP5)==
-[[3d3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3M OCA].
+<StructureSection load='3d3m' size='340' side='right'caption='[[3d3m]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3d3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3M FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3m OCA], [https://pdbe.org/3d3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3m RCSB], [https://www.ebi.ac.uk/pdbsum/3d3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3m ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IF4G2_HUMAN IF4G2_HUMAN] Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.<ref>PMID:9049310</ref> <ref>PMID:9032289</ref> <ref>PMID:11511540</ref> <ref>PMID:11943866</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/3d3m_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d3m ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[C-terminal portion of human eIF4GI|C-terminal portion of human eIF4GI]]
-*[[Death Associated Protein 5|Death Associated Protein 5]]
 *[[Death-associated protein|Death-associated protein]]
-*[[Eukaryotic initiation factor|Eukaryotic initiation factor]]
+*[[Death-associated protein 3D structures|Death-associated protein 3D structures]]
+*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
-==Reference==
+== References ==
-<ref group="xtra">PMID:018722383</ref><references group="xtra"/>
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Dym, O.]]
+[[Category: Large Structures]]
-[[Category: ISPC, Israel Structural Proteomics Center.]]
+[[Category: Dym O]]
-[[Category: Heat repeat domain]]
-[[Category: Initiation factor]]
-[[Category: ISPC]]
-[[Category: Israel Structural Proteomics Center]]
-[[Category: Phosphoprotein]]
-[[Category: Protein biosynthesis]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Repressor]]
-[[Category: Structural genomic]]
-[[Category: Translation]]
-[[Category: Translation regulation]]