3d0t: Difference between revisions

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[[Image:3d0t.png|left|200px]]


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==Structure of the BNB domain of the Hsp70 cochaperone Bag2==
The line below this paragraph, containing "STRUCTURE_3d0t", creates the "Structure Box" on the page.
<StructureSection load='3d0t' size='340' side='right'caption='[[3d0t]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3d0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D0T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d0t OCA], [https://pdbe.org/3d0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d0t RCSB], [https://www.ebi.ac.uk/pdbsum/3d0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d0t ProSAT]</span></td></tr>
{{STRUCTURE_3d0t| PDB=3d0t |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/BAG2_MOUSE BAG2_MOUSE] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d0/3d0t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d0t ConSurf].
<div style="clear:both"></div>


===Structure of the BNB domain of the Hsp70 cochaperone Bag2===
==See Also==
 
*[[BAG family proteins 3D structures|BAG family proteins 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_19029896}}
 
==About this Structure==
3D0T is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0T OCA].
 
==Reference==
<ref group="xtra">PMID:19029896</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Devlin, K.]]
[[Category: Devlin K]]
[[Category: Misra, S.]]
[[Category: Misra S]]
[[Category: Nix, J C.]]
[[Category: Nix JC]]
[[Category: Xu, Z.]]
[[Category: Xu Z]]
[[Category: 4-helix bundle]]
[[Category: Chaperone]]
[[Category: Coiled coil]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:53:27 2010''

Latest revision as of 12:39, 21 February 2024

Structure of the BNB domain of the Hsp70 cochaperone Bag2Structure of the BNB domain of the Hsp70 cochaperone Bag2

Structural highlights

3d0t is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.55Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BAG2_MOUSE Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3d0t, resolution 2.55Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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