3cm9: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:3cm9.png|left|200px]]
-<!--
+==Solution Structure of Human SIgA2==
-The line below this paragraph, containing "STRUCTURE_3cm9", creates the "Structure Box" on the page.
+<StructureSection load='3cm9' size='340' side='right'caption='[[3cm9]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3cm9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CM9 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray solution scattering</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cm9 OCA], [https://pdbe.org/3cm9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cm9 RCSB], [https://www.ebi.ac.uk/pdbsum/3cm9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cm9 ProSAT]</span></td></tr>
-{{STRUCTURE_3cm9|  PDB=3cm9  |  SCENE=  }}
+</table>
+== Function ==
-===Solution Structure of Human SIgA2===
+[https://www.uniprot.org/uniprot/PIGR_HUMAN PIGR_HUMAN] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-<!--
+Check<jmol>
-The line below this paragraph, {{ABSTRACT_PUBMED_19109255}}, adds the Publication Abstract to the page
+  <jmolCheckbox>
-(as it appears on PubMed at http://www.pubmed.gov), where 19109255 is the PubMed ID number.
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/3cm9_consurf.spt"</scriptWhenChecked>
--->
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-{{ABSTRACT_PUBMED_19109255}}
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
-==About this Structure==
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cm9 ConSurf].
-CM9 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CM9 OCA].
+<div style="clear:both"></div>
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:19109255</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Almogren, A.]]
+[[Category: Large Structures]]
-[[Category: Bonner, A.]]
+[[Category: Almogren A]]
-[[Category: Furtado, P B.]]
+[[Category: Bonner A]]
-[[Category: Kerr, M A.]]
+[[Category: Furtado PB]]
-[[Category: Perkins, S J.]]
+[[Category: Kerr MA]]
-[[Category: Constrained modelling]]
+[[Category: Perkins SJ]]
-[[Category: Glycoprotein]]
-[[Category: Iga]]
-[[Category: Immune system]]
-[[Category: Immunoglobulin c region]]
-[[Category: Immunoglobulin domain]]
-[[Category: Membrane]]
-[[Category: Mucosal immunity]]
-[[Category: Phosphoprotein]]
-[[Category: Polymorphism]]
-[[Category: Secreted]]
-[[Category: Secretory iga1]]
-[[Category: Secretory iga2]]
-[[Category: Transmembrane]]
-[[Category: X-ray and neutron scattering]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  2 16:21:47 2009''