3ccv: Difference between revisions

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-{{Large structure}}
-{{STRUCTURE_3ccv|  PDB=3ccv  |  SCENE=  }}
-===Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A===
-{{ABSTRACT_PUBMED_18455733}}
-==About this Structure==
+==Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A==
-[[3ccv]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCV OCA].
+<StructureSection load='3ccv' size='340' side='right'caption='[[3ccv]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ccv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CCV FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ccv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ccv OCA], [https://pdbe.org/3ccv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ccv RCSB], [https://www.ebi.ac.uk/pdbsum/3ccv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ccv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RL5_HALMA RL5_HALMA] This is 1 of 5 proteins that mediates the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Forms part of the central protuberance. Modeling places the A and P site tRNAs in close proximity to this protein; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. In the 70S ribosome it is thought to contact protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.[HAMAP-Rule:MF_01333_A]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cc/3ccv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ccv ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Ribosomal protein L10|Ribosomal protein L10]]
+*[[Ribosome 3D structures|Ribosome 3D structures]]
-*[[Ribosomal protein L11|Ribosomal protein L11]]
+__TOC__
-*[[Ribosomal protein L13|Ribosomal protein L13]]
+</StructureSection>
-*[[Ribosomal protein L14|Ribosomal protein L14]]
-*[[Ribosomal protein L19|Ribosomal protein L19]]
-*[[Ribosomal protein L2|Ribosomal protein L2]]
-*[[Ribosomal protein L21|Ribosomal protein L21]]
-*[[Ribosomal protein L3|Ribosomal protein L3]]
-*[[Ribosomal protein L34|Ribosomal protein L34]]
-*[[Ribosomal protein L4|Ribosomal protein L4]]
-*[[Ribosomal protein L5|Ribosomal protein L5]]
-*[[Ribosomal protein L6|Ribosomal protein L6]]
-*[[Ribosomal protein L7|Ribosomal protein L7]]
-*[[Ribosome|Ribosome]]
-==Reference==
-<ref group="xtra">PMID:018455733</ref><references group="xtra"/>
 [[Category: Haloarcula marismortui]]
-[[Category: Blaha, G.]]
+[[Category: Large Structures]]
-[[Category: Gurel, G.]]
+[[Category: Blaha G]]
-[[Category: 23s rrna]]
+[[Category: Gurel G]]
-[[Category: G2616a mutation]]
-[[Category: Large ribosomal subunit]]
-[[Category: Ribosome]]