3c96: Difference between revisions

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 ==Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240==
-<StructureSection load='3c96' size='340' side='right' caption='[[3c96]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+<StructureSection load='3c96' size='340' side='right'caption='[[3c96]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3c96]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C96 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3c96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C96 FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">phzS, PA4217 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c96 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c96 RCSB], [http://www.ebi.ac.uk/pdbsum/3c96 PDBsum], [http://www.topsan.org/Proteins/NESGC/3c96 TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c96 OCA], [https://pdbe.org/3c96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c96 RCSB], [https://www.ebi.ac.uk/pdbsum/3c96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c96 ProSAT], [https://www.topsan.org/Proteins/NESGC/3c96 TOPSAN]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHZS_PSEAE PHZS_PSEAE] Involved in the biosynthesis of pyocyanine, a blue-pigmented phenazine derivative, which plays a role in virulence. Catalyzes the oxidative decarboxylation of 5-methylphenazine-1-carboxylate (5-methyl-PCA) to pyocyanine. Can also act on phenazine-1-carboxylate (PCA), converting it into 1-hydroxyphenazine (1-HP). However, PCA is a poor substrate.<ref>PMID:17253782</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c96_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c96_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c96 ConSurf].
 <div style="clear:both"></div>
+==See Also==
+*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Pseudomonas aeruginosa pao1]]
+[[Category: Large Structures]]
-[[Category: Acton, T B.]]
+[[Category: Pseudomonas aeruginosa PAO1]]
-[[Category: Chen, Y.]]
+[[Category: Acton TB]]
-[[Category: Hunt, J F.]]
+[[Category: Chen Y]]
-[[Category: Mao, L.]]
+[[Category: Hunt JF]]
-[[Category: Montelione, G T.]]
+[[Category: Mao L]]
-[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Montelione GT]]
-[[Category: Seetharaman, J.]]
+[[Category: Seetharaman J]]
-[[Category: Tong, L.]]
+[[Category: Tong L]]
-[[Category: Vorobiev, S M.]]
+[[Category: Vorobiev SM]]
-[[Category: Wang, D.]]
+[[Category: Wang D]]
-[[Category: Xiao, R.]]
+[[Category: Xiao R]]
-[[Category: Fad]]
-[[Category: Monooxygenase]]
-[[Category: Nesg]]
-[[Category: Northeast structural genomics consortium]]
-[[Category: Oxidoreductase]]
-[[Category: Par240]]
-[[Category: Pf01266]]
-[[Category: Protein structure initiative]]
-[[Category: Psi-2]]
-[[Category: Structural genomic]]