2zd9: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2zd9.png|left|200px]]


{{STRUCTURE_2zd9|  PDB=2zd9  |  SCENE=  }}
==Structure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel==
 
<StructureSection load='2zd9' size='340' side='right'caption='[[2zd9]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
===Structure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2zd9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZD9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_18216238}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zd9 OCA], [https://pdbe.org/2zd9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zd9 RCSB], [https://www.ebi.ac.uk/pdbsum/2zd9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zd9 ProSAT]</span></td></tr>
[[2zd9]] is a 4 chain structure of [[Ion channels]] and [[Ion channels (Part II)]] with sequence from [http://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZD9 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNGK1_RHILO CNGK1_RHILO] Cyclic nucleotide-regulated potassium channel activated by cAMP.<ref>PMID:15550244</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zd/2zd9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zd9 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ion channels|Ion channels]]
*[[Ion channels 3D structures|Ion channels 3D structures]]
*[[Ion channels (Part II)|Ion channels (Part II)]]
== References ==
 
<references/>
==Reference==
__TOC__
<ref group="xtra">PMID:018216238</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mesorhizobium loti]]
[[Category: Mesorhizobium loti]]
[[Category: Cabral-Morais, J M.]]
[[Category: Cabral-Morais JM]]
[[Category: Clayton, G M.]]
[[Category: Clayton GM]]
[[Category: Membrane protein]]
[[Category: Transmembrane protein]]

Latest revision as of 12:25, 21 February 2024

Structure of a Bacterial Cyclic-Nucleotide Regulated Ion ChannelStructure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel

Structural highlights

2zd9 is a 4 chain structure with sequence from Mesorhizobium loti. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CNGK1_RHILO Cyclic nucleotide-regulated potassium channel activated by cAMP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH. Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 2004 Nov 24;119(5):615-27. PMID:15550244 doi:10.1016/j.cell.2004.10.030

2zd9, resolution 4.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2zd9&oldid=4063341"