2rks: Difference between revisions

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[[Image:2rks.png|left|200px]]


{{STRUCTURE_2rks|  PDB=2rks  |  SCENE=  }}
==Crystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperature==
 
<StructureSection load='2rks' size='340' side='right'caption='[[2rks]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
===Crystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperature===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2rks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RKS FirstGlance]. <br>
{{ABSTRACT_PUBMED_18369193}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rks OCA], [https://pdbe.org/2rks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rks RCSB], [https://www.ebi.ac.uk/pdbsum/2rks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rks ProSAT]</span></td></tr>
[[2rks]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKS OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rk/2rks_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rks ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Staphylococcal nuclease|Staphylococcal nuclease]]
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:018369193</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Garcia-Moreno, E B.]]
[[Category: Garcia-Moreno EB]]
[[Category: Harms, M J.]]
[[Category: Harms MJ]]
[[Category: Schlessman, J L.]]
[[Category: Schlessman JL]]
[[Category: Hydrolase]]
[[Category: Hyperstable variant]]
[[Category: Internal ion pair]]
[[Category: Staphylococcal nuclease]]

Latest revision as of 12:23, 21 February 2024

Crystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperatureCrystal structure of Staphylococcal nuclease variant PHS L38K at cryogenic temperature

Structural highlights

2rks is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.01Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUC_STAAU Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2rks, resolution 2.01Å

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