2qwx: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:2qwx.png|left|200px]]
-<!--
+==Crystal Structure of Quinone Reductase II==
-The line below this paragraph, containing "STRUCTURE_2qwx", creates the "Structure Box" on the page.
+<StructureSection load='2qwx' size='340' side='right'caption='[[2qwx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2qwx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QWX FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_2qwx|  PDB=2qwx  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qwx OCA], [https://pdbe.org/2qwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qwx RCSB], [https://www.ebi.ac.uk/pdbsum/2qwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qwx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qw/2qwx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qwx ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of Quinone Reductase II===
+==See Also==
+*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_18254726}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 18254726 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_18254726}}
-==About this Structure==
-QWX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QWX OCA].
-==Reference==
-<ref group="xtra">PMID:18254726</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Boutin, J A.]]
+[[Category: Large Structures]]
-[[Category: Calamini, B.]]
+[[Category: Boutin JA]]
-[[Category: Mesecar, A D.]]
+[[Category: Calamini B]]
-[[Category: Santarsiero, B D.]]
+[[Category: Mesecar AD]]
-[[Category: Cytoplasm]]
+[[Category: Santarsiero BD]]
-[[Category: Fad]]
-[[Category: Flavoprotein]]
-[[Category: Metal-binding]]
-[[Category: Oxidoreductase]]
-[[Category: Polymorphism]]
-[[Category: Qr2]]
-[[Category: Zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:58:37 2009''