2qcb: Difference between revisions

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[[Image:2qcb.png|left|200px]]


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==T7-tagged full-length streptavidin complexed with ruthenium ligand==
The line below this paragraph, containing "STRUCTURE_2qcb", creates the "Structure Box" on the page.
<StructureSection load='2qcb' size='340' side='right'caption='[[2qcb]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QCB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KYS:N-(4-{[(2-AMINOETHYL)AMINO]SULFONYL}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE-(1,2,3,4,5,6-ETA)-BENZENE-CHLORO-RUTHENIUM(III)'>KYS</scene></td></tr>
{{STRUCTURE_2qcb|  PDB=2qcb  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qcb OCA], [https://pdbe.org/2qcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qcb RCSB], [https://www.ebi.ac.uk/pdbsum/2qcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qcb ProSAT]</span></td></tr>
 
</table>
===T7-tagged full-length streptavidin complexed with ruthenium ligand===
== Function ==
 
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
[[2qcb]] is a 1 chain structure of [[Avidin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCB OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qc/2qcb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qcb ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Avidin]]
*[[Avidin 3D structures|Avidin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:18176932</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
[[Category: Creus, M.]]
[[Category: Creus M]]
[[Category: Pordea, A.]]
[[Category: Le Trong I]]
[[Category: Stenkamp, R E.]]
[[Category: Pordea A]]
[[Category: Trong, I Le.]]
[[Category: Stenkamp RE]]
[[Category: Ward, T R.]]
[[Category: Ward TR]]
[[Category: Artificial transfer hydrogenase]]
[[Category: Biotin binding protein]]
[[Category: Streptavidin]]
[[Category: T7-tag]]

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