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[[Image:2q91.jpg|left|200px]]


{{Structure
==Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor==
|PDB= 2q91 |SIZE=350|CAPTION= <scene name='initialview01'>2q91</scene>, resolution 1.630&Aring;
<StructureSection load='2q91' size='340' side='right'caption='[[2q91]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Residue+A+102'>AC1</scene>, <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+A+103'>AC2</scene>, <scene name='pdbsite=AC3:Ca+Binding+Site+For+Residue+B+103'>AC3</scene> and <scene name='pdbsite=AC4:Ca+Binding+Site+For+Residue+B+104'>AC4</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
<table><tr><td colspan='2'>[[2q91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q91 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
|GENE= S100A4, CAPL, MTS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q91 OCA], [https://pdbe.org/2q91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q91 RCSB], [https://www.ebi.ac.uk/pdbsum/2q91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q91 ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q91 OCA], [http://www.ebi.ac.uk/pdbsum/2q91 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2q91 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/S10A4_HUMAN S10A4_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q91_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q91 ConSurf].
<div style="clear:both"></div>


'''Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor'''
==See Also==
 
*[[S100 proteins 3D structures|S100 proteins 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2Q91 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q91 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Almo, S C.]]
[[Category: Almo SC]]
[[Category: Bresnick, A R.]]
[[Category: Bresnick AR]]
[[Category: Knight, D.]]
[[Category: Knight D]]
[[Category: Malashkevich, V N.]]
[[Category: Malashkevich VN]]
[[Category: Ramagopal, U A.]]
[[Category: Ramagopal UA]]
[[Category: calcium]]
[[Category: ef-hand]]
[[Category: metal binding protein]]
[[Category: metastatic tumor]]
[[Category: myosin]]
[[Category: s100a4]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:46:28 2008''

Latest revision as of 12:14, 21 February 2024

Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis FactorStructure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor

Structural highlights

2q91 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.63Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

S10A4_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2q91, resolution 1.63Å

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