2pwe: Difference between revisions

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-[[Image:2pwe.png|left|200px]]
-{{STRUCTURE_2pwe|  PDB=2pwe  |  SCENE=  }}
+==Crystal structure of the MutB E254Q mutant in complex with the substrate sucrose==
+<StructureSection load='2pwe' size='340' side='right'caption='[[2pwe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2pwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_ubonensis_subsp._mesacidophila Burkholderia ubonensis subsp. mesacidophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWE FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwe OCA], [https://pdbe.org/2pwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwe RCSB], [https://www.ebi.ac.uk/pdbsum/2pwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwe ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q2PS28_9BURK Q2PS28_9BURK]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwe_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwe ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of the MutB E254Q mutant in complex with the substrate sucrose===
+==See Also==
+*[[Trehalulose synthase|Trehalulose synthase]]
-{{ABSTRACT_PUBMED_17597061}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Burkholderia ubonensis subsp. mesacidophila]]
-[[2pwe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mesoacidophila Pseudomonas mesoacidophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWE OCA].
+[[Category: Large Structures]]
+[[Category: Aghajari N]]
-==Reference==
+[[Category: Haser R]]
-<ref group="xtra">PMID:017597061</ref><references group="xtra"/>
+[[Category: Ravaud S]]
-[[Category: Isomaltulose synthase]]
+[[Category: Robert X]]
-[[Category: Pseudomonas mesoacidophila]]
-[[Category: Aghajari, N.]]
-[[Category: Haser, R.]]
-[[Category: Ravaud, S.]]
-[[Category: Robert, X.]]
-[[Category: Alpha-amylase family]]
-[[Category: Barrel]]
-[[Category: Enzyme-substrate complex]]
-[[Category: Isomerase]]
-[[Category: Sucrose isomerase]]
-[[Category: Trehalulose synthase]]