2pa1: Difference between revisions

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OCA

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 ==Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin==
-<StructureSection load='2pa1' size='340' side='right' caption='[[2pa1]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+<StructureSection load='2pa1' size='340' side='right'caption='[[2pa1]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2pa1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PA1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2pa1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PA1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDLIM2, PP6345 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pa1 OCA], [http://pdbe.org/2pa1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2pa1 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pa1 OCA], [https://pdbe.org/2pa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pa1 RCSB], [https://www.ebi.ac.uk/pdbsum/2pa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pa1 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PDLI2_HUMAN PDLI2_HUMAN]] Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
+[https://www.uniprot.org/uniprot/PDLI2_HUMAN PDLI2_HUMAN] Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pa1_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pa1_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 24: / Line 25: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H]]
+[[Category: Large Structures]]
-[[Category: Bunkoczi, G]]
+[[Category: Arrowsmith CH]]
-[[Category: Burgess-Brown, N]]
+[[Category: Bunkoczi G]]
-[[Category: Delft, F von]]
+[[Category: Burgess-Brown N]]
-[[Category: Doyle, D A]]
+[[Category: Doyle DA]]
-[[Category: Edwards, A]]
+[[Category: Edwards A]]
-[[Category: Elkins, J]]
+[[Category: Elkins J]]
-[[Category: Papagrigoriou, E]]
+[[Category: Papagrigoriou E]]
-[[Category: Pike, A C.W]]
+[[Category: Pike ACW]]
-[[Category: Structural genomic]]
+[[Category: Salah E]]
-[[Category: Salah, E]]
+[[Category: Shrestha L]]
-[[Category: Shrestha, L]]
+[[Category: Sundstrom M]]
-[[Category: Sundstrom, M]]
+[[Category: Turnbull AP]]
-[[Category: Turnbull, A P]]
+[[Category: Ugochukwu E]]
-[[Category: Ugochukwu, E]]
+[[Category: Umeano C]]
-[[Category: Umeano, C]]
+[[Category: Uppenberg J]]
-[[Category: Uppenberg, J]]
+[[Category: Weigelt J]]
-[[Category: Weigelt, J]]
+[[Category: Von Delft F]]
-[[Category: Metal binding protein]]
-[[Category: Pdz domain]]
-[[Category: Sgc]]